5 Genetic Discoveries in 2013
Would you rather sit around watching D News tutorials all day instead of exercising Well, if so, scientific research suggests that your genes might be to blame. Hi, I'm Cristen Conger, of Stuff Mom Never Told You, for D News. And in 2013, research on genes or the cellular instruction manuals we inherit from our parents offered some fascinating insights into how those nifty DNA packages may influence our daily habits and behaviors. For starters, researchers out of the University of Missouri pinpointed a set of 36 genes that might determine how much or little we love to exercise.
After noticing how some lab rats voluntarily jogged on their wheels while others took it easy inside their cages, the researchers bred 10 generations of the active and notsoactive rats, and found that the physical activity gap persisted between those groups of great, great, great, and so forth rat grandchildren. And the most noticeable difference between those two groups those 36 laziness genes. Now in the future, though, we might have a workaround those socalled laziness genes thanks to PLIN2, better known as the obesity gene. A promising study published in early 2013 detailed.
How turning off that PLIN2 genetic expression halted weight gain, and increased activity levels in rats, even when they were being that high fat diets. Next up, scientists plan to figure out the physiological mechanisms behind that obesity gene, and how it might work in humans. Now recent digging into our DNA has revealed not only insights into our physical health, but also our emotional health. For the first time, in 2013, researchers from UC Berkeley and Northwestern University identified a gene variant, or allele, that appeared to mediate husbands' and wives' emotional sensitivity to relationship ups.
And downs. Specifically, the people who inherited two short versions of this marital bliss gene tended to report more relationship highs and lows, whereas those with long versions of the genes were more even keeled over the long term. Now undoubtedly, some couples with kids may experience more emotional highs than lows due to a newly discovered gene that triggers early, or precocious, puberty. According to a 2013 study published in the New England Journal of Medicine, a genetic mutation passed along by fathers may cause reproductive hormones to activate in kids younger than nine years old, which.
Can lead to health complications later in life, not to mention a prolonged period of hormonerelated adolescent angst. And finally, as a rare south paw, I was interested to learn about a possible genetic explanation for handedness. It turns out that right handedness, at least, may root back to embryonic genes that organize our organs, and help our bodies develop symmetrically. But unfortunately, we'll have to wait until 2014 or later to get to the bottom of why some of us go left instead of right. But enough about me, what about you.
Diseaseresistance Gene Identified in Peppers
Researches are the UC Davis Seed and Biotechnology Center have identified a candidate gene that encodes a enzyme in peppers meant to trigger resistance to a common pathogen. The pathogen Phytophthora capsici spreads the root rot disease that can severely affect crop yields in the pepper industry. Doctoral candidate Zeb Rehrig, under the direction of Allen Van Deynze, used 400 lines from four populations of peppers for the study. The effects of the pathogen on a flat of peppers is shown in this tutorial over a period of six days. This particular isolate was collected from the Northeastern part of the U.S.
Overview of the Condition High Cholesterol
Cholesterol is used by the body in several biochemical reactions necessary for life, including making new cells, and making hormones. Too much cholesterol can cause plaque to build up in blood vessels, putting patients at risk for heart attack and stroke. Factors within your control such as inactivity, obesity and an unhealthy diet contribute to high LDL cholesterol and low HDL cholesterol. Factors beyond your control may play a role, too. For example, your genetic makeup may keep cells from removing LDL cholesterol from your blood efficiently or cause your liver to produce too much cholesterol.
High blood cholesterol does not cause symptoms. Some people with rare genetic diseases that cause extremely high cholesterol may experience yellowish patches underneath the skin around the eyelids xanthelasma palpebrarum. Risk factors include smoking, obesity, having a large waist, poor diet, lack of exercise and diabetes. Blood levels of cholesterol can be controlled partially by limiting foods high in cholesterol and eating foods high in fiber, which can help remove cholesterol from the blood. Medications to control cholesterol include statins HMGCoA reductase inhibitors which have been directly associated with reduced risk for heart attack and stroke. Examples.
Why Do We Have More Boys Than Girls
Most human parentstobe assume that the sex of their child comes down to a flip of the chromosomal coin, with an equal chance of conceiving a boy or girl. But in reality, the odds aren't even for every 100 girls born, the world gains about 106 baby boys. Currently, that skewed sex ratio comes out to roughly 10 million more baby boys than girls born worldwide each year. There are some countries where human meddling stacks the odds even higher in favor of boys, but that doesn't explain the fixed odds everywhere.
Else. The intrinsic boygirl ratio is rigged by Mother Nature. In fact, it's even more rigged than birth rates show human conception results in about 150 male zygotes for every 100 females! But there's a rather tragic reason for this big biological boybias early on male fetuses are much more likely to be miscarried or stillborn than female fetuses, and boys that do make out of the womb suffer more fatal diseases, take more mortal risks, and fall prey to more violence than girls. So by the time kids grow.
Up and reach babymaking age, the ratio of males to females is just about 1 to 1. But the likelihood of a boy even making it to birth is also influenced by his mom's living conditions during pregnancy. For example, when a massive famine struck China in the early 1960s, the relative likelihood of having a son suddenly dropped until the famine ended. And male Americans born to billionaires seem to have higher than average odds of fathering sons. Somehow, female biology suppresses boys' survival in the womb during tough times and.
Boosts it when times are good. We've seen the same pattern in other mammals, too when resources are scarce, mothers give birth to fewer males than normal when resources are plentiful, they bear more. The best explanation we have for this has to do with sex the other kind. In biological terms, the whole goal of copulation is to reproduce to pass down your genes to someone who will someday pass them on again. Female offspring are almost guaranteed to reproduce, famine or no famine, because male mammals are pretty much always willing to mate. Males,.
Against Genetic Odds, A New Heart Allows Kelli Tye to Thrive
My grandmother, she wasn't officially diagnosed. They didn't really know much about HCM back then. but we know she had HCM. She had a bad heart. And then she died in her 20s. And then my mother, she was 45 when she passed away from it. I've lived with it pretty much my whole life. Hypertrophic cardiomyopathy or HCM is a genetic or inherited disorder of the cardiac muscle. It predisposes individuals to thickening of the heart muscle which can lead to a whole host of problems. and eventually, the heart will will wear out.
Considering our heart conditions, we're a very active family. We're not able to do like competitive sports or anything. But we love hiking. It's one of our favorite things. Her heart condition was picked up very early on even when we first found out she was pregnant with our daughter. We just didn't realize how bad it was. I started noticing I was getting tired really easy. I would wake up at night gasping for air. My life kind of felt like it was slipping away. I first met Kelli when in 2012.
She had been with Kaiser for a couple of years. And she had been doing well initially but then started to feel worse and worse. Dr. Carlos was my kids' cardiologist and I really liked him, and he seemed to really know a lot about HCM. He seemed to immediately know what was going on. Goes over, presses on her stomach, sees the vein bulge and he goes, So have you ever thought about getting listed for a heart transplant And surprisingly, you know, you would think I would be really scared but I thought, well, he said my heart has.
About a year left so, I guess we better get this done. She's the best thing that ever happened to me. She really is. She's tough, resilient. During the times that she went through, she kept her head up. My family stayed the night with me. And then the next morning, they wheeled me down to the OR and everybody said goodbye to me and gave me hugs and kisses and prayers and everything. I'm hiking again better than I ever did before. It's amazing. I have a lot of energy now.
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