Hello, during this talk we are going to discuss what to do or how to react to a case of urticaria/angioedema. It has been divided into four objectives. The first is to recognize the al picture, its management, know when we really have to refer a patient with urticaria or angioedema to the allergist, request an allergy.

Study and also know a little about nonurticaria angioedema. basic concepts of angioedema/urticaria. Urticaria is characterized by the appearance of bumps on any part of the body’s surface. It may or may not.

Be associated with angioedema. It normally lasts less than 24 hours, the lesions go down with vitropression, resolve with living a residual lesion. It can be divided into chronic or acute; chronic is the type that lasts more than six weeks, and acute lasts less.

Than six weeks. Diagnosing urticaria/angioedema is basically al and, contrary to popular belief, the majority of the time there is no associated respiratory involvement, and 20% of the general population can have some type of urticaria/angioedema episode in their life without it being caused by an allergic reaction,.

Or call for an allergy study. Well, speaking of possible causes 70% of the urticaria/angioedema events are idiopathic, contrary to popular belief, and only the remaining 30% are going to have a definite cause. For the children population,.

Foods are the most common cause, medications in the adult population, of these antibiotics and physical agents, cold, heat, pressure, dermographism, urticaria due to latex, hymenopterous insect bites,.

Autoimmune. And other causes are infectious processes, aquagenic urticaria, cholinergic contact urticaria or induced by exercise. Now we are going to discuss treatment.

During the acute phase of the urticaria/ angioedema episode the first recourse is antihistamines, for example intramuscular desclofeninamine or nonsedative oral antihistamines, always multiplying the dose by two;.

El Angioedema Hereditario

Hereditary angioedema (hae) is a genetic illness that causes a type of swelling known as oedemas. This process occurs in different parts of the body: in mucosal areas such as the throat, in the intestinal area, or anywhere on the skin. The frequency and intensity of these episodes often vary and depend on each person or situation. The genetic defect that causes HAE is hereditary. This means a child has a 50% chance of suffering from the disorder if his mother or father does already, although no family history of HAE does not rule out its diagnosis.

Up to 25% of all recently diagnosed hereditary angioedema cases affect people who have experienced a spontaneous mutation in their C1inhibitor gene. These patients can pass this defective gene on to their children. The main problem concerning the disease is that an enzyme, called the C1inhibitor, is not sufficiently active. The uncontrolled activation of the Complement System regulated by this enzyme causes swelling in many areas. Three types of have been identified:.

Type i: showing not enough of the c1inh enzyme in the blood. Type II: showing that the enzyme is not active enough. Type III: which was recently identified and the cause of which is unknown. It shows normal levels of the C1Inhibitor, which functions well. This type is related to oestrogen intake. The main symptom is oedema.

Skin oedema commonly affects the hands and feet, as well as the face and genitals. Pain and disfiguration caused by oedema are not immediately lifethreatening, but can be traumatic. Oedema in the pharynx, nose, or on the tongue is the most serious case. An outbreak in these areas can be fatal, possibly causing asphyxiation if airways become obstructed. When swelling occurs in the abdominal region, patients usually experience pain, cramps, nausea, and diarrhoea. Swelling from a HAE episode tends to develop gradually over many hours.

Slowly progressing during the first 12 to 36 hours and subsiding subsequently after 2 to 5 days. These episodes vary greatly in frequency, duration, severity, as well as in the areas where they occur. Therefore, it is almost impossible to predict where the next oedema episode will occur. Warning signs of a possible episode are: Tingling or flat, nonpruriginous rashes on the skin. Difficulty swallowing, swollen tongue, hoarse voice,.

Wheezing, difficulty breathing or coughing in the pharynx. Nausea, cramping or changes in bowel movements in the abdominal region. These warning signs vary from patient to patient and may not occur at all. HAE treatment is based on 3 principles: Avoiding or reducing such episodes over time. Controlling or treating those episodes that occur.

And prevention in cases of particular risk. Hereditary angioedema may seriously reduce quality of life as it requires preventive treatment in certain situations. However, patients can control symptoms and lead a normal and active life with adequate knowledge of the illness and the available treatment options. Along with the support of family and friends, connecting with other patients.

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